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Omicron wave may cut future severity of COVID disease

The Omicron variant of coronavirus may reduce the incidence of severe COVID-19 disease, and the infection may become less disruptive to individuals and society in future, according to a study conducted by researchers in South Africa.

The findings of the yet-to-be peer-reviewed study are consistent with the previous observations of Omicron displacing Delta, since the variant can elicit immunity which neutralises Delta.

The researchers from Africa Health Research Institute observed in samples from 23 people infected with Omicron in November and December that the variant escapes neutralising immunity elicited by Delta infection.

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This indicates that Omicron can re-infect Delta infected individuals but not vice-versa, giving Omicron an advantage over Delta, they said."The implications of such displacement would depend on whether Omicron is indeed less pathogenic than Delta. If so, then the incidence of COVID-19 severe disease would be reduced and the infection may shift to become less disruptive to individuals and society," they authors of the study noted.

The finding is an update to the study by the same research team which found enhancement of immunity against Delta variant with Omicron infection.

"We were able to add study participants to see more clearly the effect of vaccination," Professor Alex Sigal, from Africa Health Research Institute tweeted on Tuesday.

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