Global Alagille Syndrome Market

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Global Alagille Syndrome Market was valued US$ XX Mn in 2019 and is expected to reach US$ XX Mn by 2027, at a CAGR of 6.12 % during a forecast period.

 

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Alagille syndrome is a genetic disorder affecting body parts like liver, heart, etc. People with Alagille syndrome have less number of bile ducts inside the liver.

Alagille syndrome is an exceptional autosomal leading genetic disorder that affects many organ systems of the body usually in the skeleton, liver, eyes, kidneys, and heart. Alagille syndrome is initiated by either change in the JAG1 gene or deletion in gene material on chromosome 20 that contains the JAG1 genetic factor. These proteins are essential for Notch signalling between neighbouring cells throughout embryonic development and error in genetic factor results in abnormalities in the heart, bile ducts, certain facial features, and spinal column.

As per the US Department of Health and Human Services statistics published, an expected annual prevalence of Alagille syndrome globally is 1 in 70000 newborns. Introduction of new drugs for Alagille syndrome treatment and advanced healthcare infrastructure is driving the growth of Alagille syndrome market. The MMR report covers all the trends and technologies playing major role in the growth of the Alagille syndrome market over the period 2019-2027. It highlights the opportunities, drivers, restraints, and challenges expected to influence the market growth throughout the forecast period.

Also, the MMR report will provide an accurate prediction of the contribution of various segments to the growth of the Alagille syndrome market size. By treatment, medication segment of Alagille syndrome is expected to grow at the highest CAGR of XX.78% and is expected to reach a value of US$ XX Mn. by 2027. Medications may be given to upsurge bile flow and lessen itching.

Liver transplantation only needs to be considered for Alagille syndrome patients of small-group. It may be essential if there is a severe liver disease affecting cirrhosis or there are symptoms which can’t be precise in other ways. Liver transplantation for kids with Alagille syndrome can be further complex than other liver transplants since kids with Alagille syndrome may also have problems affecting the kidneys or heart.

North America Alagille syndrome market was valued US$ XX Mn. in 2019 and is expected to reach a value of US$ XX Mn. by 2027, with a CAGR of XX.20% during the forecast period. This is attributed to the growing prevalence of rare genomic disease and well-developed healthcare industry. Along with the project of Global Genes, genetic and rare diseases affect 1 in 10 people in the U.S. However, Europe stood the second largest in the Alagille syndrome market owing to mounting prevalence of several liver diseases. In England, as per the Public Health, nearly 11,597 numbers of people died with an essential cause of liver disease in 2014.

The report focuses on international major leading industry players of Alagille syndrome market providing information such as company profiles, revenue, and other related information. In 2019, Mirum Pharmaceuticals Company presented a phase-2 ICONIC clinical trial studies data at the Global Liver Congress-2019 for maralixibat for the Alagille syndrome treatment. The trial has recognized the well-tolerated dose with no thoughtful adverse events along with durable developments in serum bile acids and itch severity in children with Alagille syndrome.

The objective of the report is to present a comprehensive analysis of the Global Alagille Syndrome Market including all the stakeholders of the industry. The past and current status of the industry with forecasted market size and trends are presented in the report with the analysis of complicated data in simple language. The report covers all the aspects of the industry with a dedicated study of key players that includes market leaders, followers, and new entrants by region. PORTER, SVOR, PESTEL analysis with the potential impact of micro-economic factors by region on the market has been presented in the report. External as well as internal factors that are supposed to affect the business positively or negatively have been analyzed, which will give a clear futuristic view of the industry to the decision-makers.

The report also helps in understanding Global Alagille Syndrome Market dynamics, structure by analyzing the market segments and projects the Global Alagille Syndrome Market size. Clear representation of competitive analysis of key players by Application, price, financial position, Product portfolio, growth strategies, and regional presence in the Global Alagille Syndrome Market make the report investor’s guide.
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Global Alagille Syndrome Market, By Treatment

• Medication
• Surgery
o Liver Transplantation
o Kidney Surgery
o Others
Global Alagille Syndrome Market, By Drugs

• Ursodeoxycholic Acid
• Cholestyramine
• Rifampin
• Naltrexone
• Others
Global Alagille Syndrome Market, By Diagnosis

• Blood Test
• Urinalysis
• Others
Global Alagille Syndrome Market, By End Users

• Hospitals
• Homecare
• Specialty Clinics
• Endocrinologists
• Others
Global Alagille Syndrome Market, By Region

• Asia Pacific
 India
 China
 Japan
 South Korea
 Australia
 Indonesia
 Malaysia
 Vietnam
 Rest of Asia
• North America
 U.S.
 Canada
• Europe
 U.K
 Germany
 France
 Russia
 Spain
 Italy
 Sweden
• South America
 Mexico
 Brazil
 Rest of South America
• Middle East & Africa
 GCC
 South Africa
 Rest of MEA
Key players operating in Global Alagille Syndrome Market

• Albireo Pharma, Inc
• Mirum Pharmaceuticals
• Teva Pharmaceutical Industries Ltd
• Zydus Cadila
• ALLERGAN
• Endo Pharmaceuticals Inc
• ANI Pharmaceuticals, Inc
• Mylan N.V.
• Glenmark Pharmaceuticals Ltd
• Amneal Pharmaceuticals LLC
• Epic Pharma, LLC
• Lannett
• Fresenius Kabi AG
• Lannett
• Novartis AG
• Pfizer, Inc
• Lupin
• Hikma Pharmaceuticals PLC
• Akorn

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