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There are case reports of patients who developed increased BUN, serum creatinine and serum potassium furosemide levels, and weight gain when furosemide was used in conjunction with NSAIDs . One study in furosemide lasix side effects furosemide 20 mg uses what is furosemide used for in humans furosemide six subjects demonstrated that the combination of furosemide and acetylsalicylic acid temporarily reduced creatinine clearance in patients with chronic renal insufficiency .
High doses ( > 80 mg) of furosemide may inhibit the binding of thyroid hormones to carrier proteins and furosemide result in transient increase in free thyroid hormones, followed by an overall decrease in total thyroid hormone levels .

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