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In addition, more metronidazol than ten randomized placebo-controlled clinical trials enrolled more than 5000 pregnant women to assess the use of antibiotic treatment (including metronidazole) for bacterial vaginosis on the incidence of preterm delivery . Many studies included first metronidazol trimester exposures . Three studies conducted to assess the risk metronidazol of infant cancer following metronidazole exposure during pregnancy did not show an increased risk; however, the ability of these studies to detect such a signal was limited . One study showed an increased risk of cleft lip, with or without cleft palate, metronidazol in infants exposed to metronidazole in-utero; however, these finding were not confirmed . There are published data from case-control studies, side effects of flagyl and alcohol flagyl 200mg dosage allergic to flagyl what else can i take cohort studies, and 2-meta-analyses that include more than 5000 pregnant women who used metronidazole during pregnancy . There metronidazol are no adequate and well-controlled studies of FLAGYL ER in pregnant women . Most studies did not show an increased risk for congenital anomalies or other adverse fetal outcomes following metronidazole exposure during metronidazol pregnancy .
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