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Patients were eligible if they had 2 or 3 levels of overexpression (based on a 0 to 3 scale) by immunohistochemical assessment of tumor tissue performed by a central testing lab.

These updated survival analyses support the demonstrated efficacy of lapatinib in the TTP analysis in this heavily pretreated population.

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Complete surgical resection is one of the most important factors for cure or extended survival, as incomplete resection of the tumor or spill of tumor cells during the operative procedure greatly increases the chance for recurrence, and drastically reduces the prognosis.

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Tell your doctor right away if you notice any signs of serious bleeding.

Mechanisms of cancer drug resistance.

The clinical situation is most critical in patients who have not yet started antibiotic treatment.

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Nevertheless, the most suitable therapeutic regimen for this group of patients is still pending and future studies particularly designed for this elderly population are needed.

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Although capecitabine has theoretical advantages in the pharmacokinetics, such as higher intratumoral and lower systemic concentration, relative to bolus 5-fluorouracil (5-FU), outcomes of chemoradiotherapy (CRT) with capecitabine or bolus 5-FU have not been directly compared in patients with locally advanced pancreatic cancer.

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The important thing in science is not so much to obtain new facts as to discover new ways of thinking about them.

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Molecular Targeted Drugs in the Developmental Stage.

Forrer F, Uusijarvi H, Waldherr C, Cremonesi M, Bernhardt P, Mueller-Brand J, et al.

This increase in FBAL concentration was thought to be due to an age-related decrease in renal function.

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Complete Pathological Response in a Patient with Metastatic Esophageal Cancer Treated with a Regimen of Capecitabine, Oxaliplatin and Docetaxel: A Case Report.

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This might be followed by more chemotherapy.

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The protocol was reviewed and approved by the National Institutes of Health Institutional Biosafety Committee, the NCI Institutional Review Board, the National Institutes of Health Office of Biotechnology Activities, and the Food and Drug Administration (all Bethesda, MD).

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