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Aplenzin unfortunately did not work for me. I have panic disorder which then sent me into a horrible state of depression. My psychiatrist first prescribed me Wellbutrin SR which I was taking twice a day. After about 3 months I started having moments where I was actually happy to be alive. At my next appointment, my psychiatrist asked if I would be intereseted in trying Aplenzin because it only needs to be taken once a day. I started off on 348 mg for three months. This was not working so he switched me to 522 mg. Two months later it is still not working. I spoke to my pharmacist who told me that I have been patient enough and if it is going to work it would have done so by now.

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